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insoluble

/ɪnˈsɑljəbəl/ noun C2
  1. Any substance that cannot be dissolved.

Plural insolubles

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However, I will only say at the present stage that your problem does not appear to me to be insoluble, and that you may expect to find us at Victoria at two o'clock."
The Case-Book of Sherlock Holmes, p. 59 · B2
It is a most insoluble mystery.”
The Memoirs of Sherlock Holmes, p. 68 · B2

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Words, meanings, pronunciations and translations from Wiktionary (CC BY-SA 4.0); how common each word is from wordfreq. Made into this dictionary by FluentPlex.