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malady

/ˈmæl.ə.di/ noun B2
  1. Any ailment or disease of the body; especially, a lingering or deep-seated disorder.
  2. A moral or mental defect or disorder.

Plural maladies

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Did you forget that this great man, this hero, this demigod, is attacked with a malady of the skin which worries him to death, prurigo?”
The Count of Monte Cristo, p. 91 · C1
This malady admits but of one remedy; I will tell you what that is.
The Count of Monte Cristo, p. 177 · C1
Since the first attack I experienced of this malady, I have continually reflected on it.
The Count of Monte Cristo, p. 181 · C1
These horrible chills, which make my teeth chatter and seem to dislocate my bones, begin to pervade my whole frame; in five minutes the malady will reach its height, and in a quarter of an hour there will be nothing left of me but a corpse.”
The Count of Monte Cristo, p. 205 · C1

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Words, meanings, pronunciations and translations from Wiktionary (CC BY-SA 4.0); how common each word is from wordfreq. Made into this dictionary by FluentPlex.