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malignancy

/məˈlɪɡ.nən.si/ noun C2
  1. The state of being malignant or diseased. (countable, uncountable)
  2. A malignant cancer; specifically, any neoplasm that is invasive or otherwise not benign. (countable, uncountable)
  3. That which is malign; evil, depravity, malevolence. (countable, uncountable)

Plural malignancies

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Somewhere there, on that desolate plain, was lurking this fiendish man, hiding in a burrow like a wild beast, his heart full of malignancy against the whole race which had cast him out.
The Hound of the Baskervilles, p. 67 · C1

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Words, meanings, pronunciations and translations from Wiktionary (CC BY-SA 4.0); how common each word is from wordfreq. Made into this dictionary by FluentPlex.