refractory
/ɹɪˈfɹæk.təɹ.i/ adjective C2- Obstinate and unruly; strongly opposed to something.
- Not affected by great heat.
- Resistant to treatment; not responding adequately to therapy.
- Incapable of registering a reaction or stimulus.
From the library
MARILLA said nothing to Matthew about the affair that evening; but when Anne proved still refractory the next morning an explanation had to be made to account for her absence from the breakfast table.
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