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malignant

/məˈlɪɡnənt/ adjective C1
  1. Harmful, malevolent, injurious. · malignant temper; malignant revenge; malignant infection
  2. Tending to produce death; threatening a fatal issue. · malignant diphtheria· a malignant tumor
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This malignant and terrible contortion, combined with the low forehead, blunt nose, and prognathous jaw gave the dead man a singularly simious and ape-like appearance, which was increased by his writhing, unnatural posture.
A Study in Scarlet, p. 29 · B2
If ever human features bespoke vice of the most malignant type, they were certainly those of Enoch J.
A Study in Scarlet, p. 45 · B2
Often it was only the smallest trace, Watson, the faintest indication, and yet it was enough to tell me that the great malignant brain was there, as the gentlest tremors of the edges of the web remind one of the foul spider which lurks in the centre.
The Return of Sherlock Holmes, p. 33 · C1
‘He was more like a malignant and cunning ape than a human being,’ said she, ‘and he always was, ever since he was a young man.’
The Return of Sherlock Holmes, p. 49 · C1

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Words, meanings, pronunciations and translations from Wiktionary (CC BY-SA 4.0); how common each word is from wordfreq. Made into this dictionary by FluentPlex.